What is the issue with Covishield vaccine?

 The makers of the Covishield Covid vaccination, AstraZeneca, have made the startling admission that thrombosis with thrombocytopenia syndrome (TTS) could be an adverse effect. Social media users are debating the vaccine's safety in response to this admission. While worries are legitimate, it's important to separate fact from myth.

Does The Covishield is dangerous..?

Many internet statements claim that Covishield puts individuals at danger for TTS, and they criticize the Indian government for allowing it. The Healthy Indian Project (THIP) verify the facts, however, indicates that although there is a chance of TTS, it is extremely rare.

TTS: What is it...?

Thrombosis with Thrombocytopenia Syndrome (TTS) is a dangerous illness marked by the production of clots in the blood with low levels of platelets. Breathlessness, headaches and migraines discomfort in the chest, and simple clotting are some of the indications. AstraZeneca has confirmed a transient connection between TTS and its vaccination.

Relationship to Covishield 

The vaccine developed by AstraZeneca and produced by the Serum Institute of India is the same as the Covishield. The two medicines are viral vectors and have been shown to be 60–80% effective against Covid-19.

Does Covishield cause the TTS side effect exclusively ?

TTS is linked to the Janssen vaccination from Johnson & Johnson in addition to the AstraZeneca vaccine. This connection has been noted by earlier research. Most vaccinations have mild side effects, like momentary fever and discomfort, which are rather frequent. These effects, though, are fleeting. Most medical specialists think that vaccinations have considerably more advantages than disadvantages.

The World Health Organization (WHO) website states that vaccinations are quite safe. Vaccines can have negative effects just like any other medication. But these are typically quite slight and transient, like an arm ache or a low-grade fever. Although incredibly rare, severer consequences are conceivable."

Do you need to worry? 

Yes, to a certain degree. But there's nothing to be alarmed about. It is noteworthy that the majority of commonly delivered vaccine in the country is Covishield, which represents the Indian version of the AstraZeneca vaccine. There aren't many TTS instances that have been identified in India. The spotlight of the media would become drawn if TTS-related deaths became common after immunization.

Furthermore, it is imperative to recognize that vaccine-induced immune thrombotic thrombocytopenia (VITT) and thrombosis with thrombocytopenia syndrome (TTS) are extremely unusual complications which usually appear after the initial vaccination.

Claims that imply that TTS is a serious threat to every one of Indians and blame it on government negligence are blatantly false and deceptive.

Reliable knowledge regarding vaccinations is provided by the Healthy Indian Project (THIP), a part of the World Health Organization's Vaccine Safety Net (VSN). THIP has fact-checked a number of statements that have been making the rounds on social media concerning COVID-19 immunizations, disproving allegations that the shots are poisonous, detrimental rather than preventative in nature or injure the brain.

How do I respond if I experience uncommon side effects? 

While immunizations have been shown to be quite safe and successful in containing the COVID-19 pandemic, there is a very small possibility of extremely rare side effects such as TTS and VITT. To manage such conditions, early recognition and management are essential.

It is an uncommon event that follows some vaccines and other causes, according to Dr. Jayadevan, Co-Chairman of the National Indian Medical Association (IMA) Covid Task Force in Kerala. Furthermore, after vaccination, TTS instances that have been recorded typically show symptoms a few weeks later. As a result, if you are having TTS symptoms, it is best to be on the lookout and get medical help.

Post-vaccination, mild side effects are typical but pass quickly. Bad consequences are not common.

Remarks from AstraZeneca

An admission by AstraZeneca about the possibility that its COVID-19 vaccination could cause TTS was made public by The Telegraph. Serum Institute of India manufactured the vaccine, which is sold globally under many names as Vaxzevria and Covishield. Utilizing a modified chimpanzee adenovirus to transfer the COVID-19 spike protein into human cells, Covishield is based on the viral vector platform, in contrast to mRNA vaccines.

According to a 2023 Yale Medicine.org research, blood clots are dangerous, especially when they form inside blood vessels and result in thrombosis. Hematologist Robert Bona, MD, of Yale Medicine clarified, "Those clots usually arise in people who are hospitalized, immobile, or have other medical conditions associated to inflammation, infection, or malignancy."

TTS was identified as a new adverse event in 2023 by the World Health Organization (WHO) in individuals who received COVID-19 non-replicant adenovirus vector-based vaccines, such as the Johnson & Johnson (J&J) Janssen COVID-19 Ad26.COV2-S vaccine and the AstraZeneca COVID-19 ChAdOx-1 vaccine.


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